
Amy Schumer’s experience with Mounjaro has been vastly different from when she tried an alternative weight-loss medication years ago.
Schumer, 43, praised the effects of Mounjaro (also known as tirzepatide) in a video clip shared on Instagram with her nearly 13 million followers.
In a previous attempt to lose weight, the comedian experienced debilitating side effects while using Ozempic for weight-loss purposes.
AMY SCHUMER SHARES SCARY SIDE EFFECT FROM OZEMPIC THAT LEFT HER BEDRIDDEN

Amy Schumer praised Mounjaro after suffering from nasty side effects of Ozempic. (Todd Owyoung)
« I wanted to share and keep it 100 with you, that years ago – and yes, this is completely unsafe to be driving and making a video – years ago, three years ago, I tried WeGovy and I was like puking, » Schumer said in the clip captured while she was behind the wheel.
« I couldn’t handle it. I don’t know if they’ve changed the formula or whatever … but anyway, I went on this telehealth meeting with MidiHealth, and it was cheap. I wanted to try it myself, cause I wanted to recommend it to my friends who are like nurses and teachers. »
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In addition to the injectable medication, which is primarily used to treat type 2 diabetes, the « Trainwreck » star has a new routine which includes hormones.
« They put me on estrogen and progesterone because I realized I was in perimenopause and my symptoms of being in perimenopause have disappeared, » Schumer said.
« My hair is fuller, my skin is better, I have more energy, I want to get down more if you know what I mean – I’m talking about sex. »

Schumer said she wanted to « keep it 100 » with her fans. (Nathan Congleton)
She added, « So that’s been great, Mounajro’s been great … I’m having a really good experience with it and I wanted to keep it real with you about that. »
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Schumer admitted she had such a good experience with the telemedicine company that she also invested in MidiHealth.
She signed off her video with a question about the royals, and asked, « I’m not going to stir the pot, but why don’t we have to call Kate Middleton Kate of Wales? Ok, Hilaria. Out. »
Earlier this year, the « Kinda Pregnant » actress told Howard Stern that she was forced to quit Ozempic due to terrible side effects.

Schumer previously detailed her negative experiences with a different weight loss drug. (Will Heath/NBC via Getty Images)
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« I have this gene – GDF15 – which makes you extremely prone to nausea which is why I was so sick during my pregnancy. So, I tried Ozempic almost three years ago and I was like bedridden, I was vomiting and then you have no energy but other people take it and they’re all good, » she said on « The Howard Stern Show. »
« I lost 30 pounds so quick, » she said. « I looked great and I couldn’t lift my head off the pillow, so what’s the point? »
Ozempic, which is a semaglutide injection, was originally approved by the U.S. Food and Drug Administration for the treatment of Type 2 diabetes, but the medication has increasingly been prescribed off label for weight loss, along with several other similar medications.
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